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MAY 14 2026
APPROVED · 78 DAYS AGO

AstraZeneca Fasenra (benralizumab) $AZN

for Hypereosinophilic Syndrome

BLA

FDA approved AstraZeneca's Fasenra for adult and pediatric patients aged 12+ with hypereosinophilic syndrome without an identifiable non-hematologic cause.

About

Hypereosinophilic syndrome is a condition where the body produces too many eosinophils, a type of white blood cell, which can damage the heart, nerves, or bone marrow. Fasenra (benralizumab) is an antibody that binds to a specific receptor on eosinophils, marking them for rapid depletion by the immune system. By directly and quickly removing these excess cells, Fasenra may help control the tissue damage that defines this serious disease.

Pivotal trial

PONENTE Phase 3 completed NCT03557307

This is a study designed to evaluate efficacy and safety of Benralizumab in reducing the Oral Corticosteroid (OCS) use in adult patients with severe asthma who are receiving OCS with or without additional asthma controller medications.

Source: ClinicalTrials.gov

Also in development