About

Lung cancer starts when genetic damage to airway cells — often from cigarette smoke or harmful chemicals — lets those cells multiply out of control and form a tumor that can spread throughout the lungs and eventually to other parts of the body. Zipalertinib is an oral medicine that blocks a specific mutated version of the EGFR protein, called an exon 20 insertion, which drives some lung tumors to grow. Because that mutation is what keeps these cancer cells dividing, shutting it down may help slow or stop the disease.