SEP 18 2026
Nuvalent — zidesamtinib $NUVL
for TKI-pretreated advanced ROS1-positive non-small cell lung cancer
Accepted NOV 19 2025.
for TKI-pretreated advanced ROS1-positive non-small cell lung cancer
Accepted NOV 19 2025.
Non-small cell lung cancer (NSCLC) is the most common form of lung cancer, often resistant to chemotherapy and typically treated with surgery when possible. Zidesamtinib is a next-generation targeted drug that selectively blocks ROS1, a cancer-driving protein, while also reaching tumors in the central nervous system. By inhibiting ROS1 more precisely than older treatments, it may help control advanced NSCLC that has progressed after prior therapy.