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JUL 22 2026
APPROVED · 9 DAYS AGO

GSK Jideytro (zidesamtinib) $GSK

for TKI-pretreated advanced ROS1-positive non-small cell lung cancer

NDA · Standard Review

About

Non-small-cell lung cancer is the most common form of lung cancer and is often treated with surgery when possible, but many advanced cases are difficult to treat with standard chemotherapy. Zidesamtinib (Jideytro) is a pill that enters the brain and selectively blocks the ROS1 protein, which drives tumor growth, in cancer cells. For people whose advanced lung cancer has continued to grow after prior ROS1-targeted therapy, this targeted approach may offer a new way to control the disease.