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AUG 26 2026
APPROVED · 34 DAYS AGO

Revolution Medicines, Inc. — Rasonque (daraxonrasib) $RVMD

for previously treated metastatic pancreatic ductal adenocarcinoma

NDA · Breakthrough · Orphan · Commissioner's National Priority Voucher (CNPV)

About

Pancreatic ductal adenocarcinoma is the most common form of pancreatic cancer and one of the deadliest solid tumors, with fewer than one in ten people alive five years after diagnosis. Rasonque is an oral medicine that binds RAS proteins while they are switched on, blocking the growth signals that keep tumor cells dividing. Because most pancreatic tumors are driven by RAS mutations, shutting down that signal could potentially slow tumor growth in people whose cancer has already been treated.

Pivotal trial

RASolute 302 Phase 3 active not recruiting NCT06625320

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard(s) of care (SOC) treatment.

Source: ClinicalTrials.gov

Also in development