FEB 19 2027
Sedana Medical AB — Sedaconda (isoflurane)
for ICU sedation of mechanically ventilated adult patients
Accepted AUG 19 2026.
About
Sedaconda delivers the inhaled anesthetic isoflurane directly to the lungs of a sedated patient using a specialized device attached to a ventilator. This method provides continuous sedation from a vapor, unlike standard intravenous drugs like propofol. For adults on mechanical ventilation in the ICU, this inhaled approach may offer a different path to maintaining calm while potentially affecting long-term recovery.
Drug Watch — recent news on Sedaconda
- Inhaled isoflurane for sedation of mechanically ventilated children in intensive care (IsoCOMFORT): a multicentre, randomised, active-control, assessor-masked, non-inferiority phase 3 trial - The Lancet
- Inhaled isoflurane via the anaesthetic conserving device versus propofol for sedation of invasively ventilated patients in intensive care units in Germany and Slovenia: an open-label, phase 3, randomised controlled, non-inferiority trial - The Lancet