SEP 9 2026
Seikagaku Corporation — Hernicore (condoliase) $4548.T
for radicular leg pain associated with lumbar disc herniation
for radicular leg pain associated with lumbar disc herniation
Lumbar disc herniation happens when the cushion between two spinal bones bulges or tears, pressing on nearby nerves and causing back pain, leg pain, numbness, and disability. Hernicore (condoliase) is a bacterial enzyme injected once into the disc, where it breaks down chondroitin sulfate, the gel-like material that gives the disc's soft center its bulk. Softening that core may lower pressure on the pinched nerve root and could ease radicular leg pain without surgery.
This study is to evaluate the effectiveness of a single-dose intervertebral disc injection of SI-6603 in subjects with lumbar disc herniation (LDH)
Source: ClinicalTrials.gov