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JUL 7 2026
UPCOMING · 34 DAYS TO PDUFA

Vera Therapeutics atacicept $VERA

for IgA nephropathy

BLA · Priority Review

Accepted JAN 7 2026.

About

IgA nephropathy is a kidney disease where the immune system mistakenly attacks the kidney's filtering units, causing inflammation that can spread to other organs. Atacicept is a lab-made protein that blocks two immune signals (BLyS and APRIL) that trigger harmful antibody production. By targeting these signals, the drug may slow the kidney damage that leads to organ complications.

Pivotal trial

ORIGIN 3 Phase 3 active not recruiting NCT04716231

A Phase 3 Study with Atacicept in Subjects With IgA Nephropathy (ORIGIN 3)

Source: ClinicalTrials.gov

Also in development