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DEC 1 2026
UPCOMING · 123 DAYS TO PDUFA

Vertex Pharmaceuticals Incorporated povetacicept $VRTX

for IgA nephropathy

BLA · Priority Review · Accelerated Approval

About

IgA nephropathy is a kidney disease where the immune system causes inflammation in the kidney's filtering units, and it can also harm other organs like the liver and skin. Povetacicept is an experimental drug designed to block specific immune signals involved in the disease process. By targeting this pathway, the drug may reduce damaging inflammation in the kidneys and slow the progression of organ damage.

Pivotal trial

NCT06564142 Phase 3 active not recruiting NCT06564142

The purpose of this study is to evaluate the efficacy of povetacicept in adult participants compared with placebo in reducing proteinuria and preserving renal function.

Source: ClinicalTrials.gov

Also in development