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Q&A Step 4 (Feb 2022)

ICH E14/S7B Q&As — Clinical and Nonclinical Evaluation of QT/QTc Interval Prolongation

E14/S7B Q&As International Council for Harmonisation
ABSTRACT — EDITORS' SUMMARY

Formal Q&A companion to E14 (clinical) and S7B (nonclinical) covering QT/QTc study design, methodology, gender, positive controls, and integration with hERG assay data. Peripheral to GCP-inspection scope but the only formal E14 Q&A published by ICH.

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OPEN ON ICH
METADATA
TypeQ&A
Year2022
VersionStep 4 (Feb 2022)
StatusCurrent
FormatPDF
Pages
Size
Last reviewedFEB 2022
SOURCE
PDF · CANONICAL LINK https://database.ich.org/sites/default/files/E14-S7B_QAs_Step4_2022_0221.pdf
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