Differin Epiduo Acne Gel cleared for nonprescription use

Sponsor: Galderma $GALD
Drug: Differin Epiduo Acne Gel · adapalene/benzoyl peroxide
Indication: acne

What this means

Differin Epiduo is a combination acne gel containing adapalene and benzoyl peroxide, which work together to unclog pores and reduce bacteria. The FDA just moved this prescription-strength acne treatment to over-the-counter status, allowing people to buy it without a doctor's note. This change could make effective acne care more accessible for teens and adults who previously needed a prescription for this type of medication.

Read original at accessdata.fda.gov ↗

Background Drug-class context · Wikipedia

Adapalene, sold under the brand name Differin among others, is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions. Studies have found adapalene is as effective as other retinoids, while causing less irritation. It also has several advantages over other retinoids. The adapalene molecule is more stable compared to tretinoin and tazarotene, which leads to less concern for photodegradation. It is also chemically more stable compared to the other two retinoids, allowing it to be used in combination with benzoyl peroxide. Due to its effects on keratinocyte proliferation and differentiation, adapalene is superior to tretinoin for the treatment of comedonal acne and is often used as a first-line agent. The Swiss company Galderma developed adapalene.

Source: Wikipedia · CC BY-SA

Topic acne treatment

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