SILVER SPRING
Ziihera regimens cleared for first-line HER2+ gastroesophageal adenocarcinoma
- Sponsor
- Jazz Pharmaceuticals plc $JAZZ
- Drug
- Ziihera · zanidatamab-hrii
- Indication
- First-line treatment of HER2-positive advanced gastroesophageal adenocarcinoma
FDA approves two zanidatamab-hrii-containing regimens for first-line treatment of adults with HER2-positive advanced gastroesophageal adenocarcinoma.
What this means
Ziihera is a targeted antibody drug that attaches to the HER2 protein on certain cancer cells. The FDA has approved its use, combined with the immunotherapy tislelizumab and chemotherapy, as an initial treatment for advanced HER2-positive stomach and esophageal cancers. This approval provides a new, first-line combination therapy option for patients with these aggressive cancers.
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